منابع مشابه
Studies in Sensitization to Skin
1. Techniques for the preparation of skin antigen suitable for intramuscular injection in rabbits, and of skin antigens (autolysate) for serological experiments are described. 2. A method was evolved which produced a soluble skin antigen (autolysate) suitable for performing precipitin tests. 3. Injection of the rabbit skin antigen and of staphylococcus toxin in rabbits resulted in the formation...
متن کاملSkin Sensitization to Remiderm and Cross-sensitization to Hydroxyquinoline Compounds.
EDITSHAL and usually, as in the present case, constructional apraxia will be detected with or without ideational apraxia, alexia, or sensory agnosia. Interpretation of Gerstmann's syndrome as an easily demonstrated and memorable pointer to diffuse cerebral damage accords well with this case, where there is no reason to suspect a highly focal lesion. Gerstmann's syndrome does not seem to have be...
متن کاملMechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity.
Twenty organic Salmonella mutagens, seven of which (including benzo[a]pyrene) are established skin carcinogens, and one of which (2-chloroethanol) is a well-defined noncarcinogen to skin, have been evaluated for skin-sensitizing activity using the local lymph node assay. The relative mutagenicity of the agents to Salmonella was also established. Fourteen of the chemicals were positive in the lo...
متن کاملPredictive identification of human skin sensitization thresholds.
For years, methods have been available for the predictive identification of chemicals that possess the intrinsic potential to cause skin sensitization. However, many have proven less suitable for the determination of relative sensitizing potency. In this respect, the local lymph node assay (LLNA) has been shown to have a number of important advantages. Through interpolation of LLNA dose-respons...
متن کاملSkin Sensitization in Chemical Risk Assessment
Anne Marie Api Research Institute for Fragrance Materials, Inc. (RIFM), Woodcliff Lake, New Jersey, USA J.H.E. Arts TNO Quality of Life, Zeist, Netherlands Harmonization Project Document No. 5 4 David Basketter Unilever Safety and Environmental Assurance Centre, Sharnbrook, Bedford, United Kingdom Jonathan Chen Antimicrobials Division, Office of Pesticide Programs, Environmental Protection Agen...
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ژورنال
عنوان ژورنال: Human & Experimental Toxicology
سال: 2015
ISSN: 0960-3271,1477-0903
DOI: 10.1177/0960327115601760